实验动物科学 ›› 2025, Vol. 42 ›› Issue (1): 87-90.DOI: 10. 3969 / j. issn. 1006-6179. 2025. 01. 016

• 综述 • 上一篇    下一篇

实验动物隔离环境设施应用管理

  

  1. (首都医科大学实验动物部,北京 100069)
  • 收稿日期:2023-07-10 出版日期:2025-02-28 发布日期:2025-03-21
  • 通讯作者: 卢 静( 1969—) ,女,教授,博士,主要从事动物模型研究及实验动物管理工作,E-mail:lujing@ ccmu. edu. cn。
  • 作者简介:张 洁( 1988—) ,女,主管技师,从事实验动物饲养繁育保种,常规实验技术服务,E-mail:angellena. student@ sina. com。
  • 基金资助:
    国家重点研发计划( 2021YFF0702805) 。

Application Management of Laboratory Animal Isolation Environmental Facilities

  1. (Department of Laboratory Animal Science,Capital Medical University, Beijing 100069,China)
  • Received:2023-07-10 Online:2025-02-28 Published:2025-03-21

摘要: 随着人类疾病动物模型的广泛应用,各高校和研究所不可避免会引入实验动物。 为防止引入过程中因应激 导致的实验动物免疫力下降而可能发生的隐性感染显性化,进而感染其他动物,应设立隔离设施,对引入动物进行 隔离检疫和观察。 我们通过在普通环境中加装隔离器的方式建立了隔离环境设施。 通过对设施的合理布局、加强 消毒灭菌、制定标准操作流程并严格执行,使运行操作更顺畅、安全,提高工作效率,保障动物品质。

关键词: 隔离环境设施, 隔离环境, 隔离器, 生物安全柜

Abstract: With the wide application of animal models of human diseases, it is inevitable that laboratory animals will be introduced by universities and research institutes. In order to prevent the potential dominance of implicit infection in laboratory animals caused by stress during the introduction process, which can lead to infection with other animals, isolation facilities should be set up to isolate, quarantine, and observe the introduced animals. We have established the isolation system facility by installing isolators in ordinary environments. Through reasonable layout of facility, strengthening disinfection and sterilization, formulation of standard operation procedures, and strict implementation, we can ensure smoother and safer, improve work efficiency, and ensure the quality of animals.

Key words: isolation system facility, isolation system, isolator, biosafety cabinet

中图分类号: